Childhood
Tsubame's father attempted to kill the Hokage (Sarutobi) when Tsubame was 2. At age 5, Tsu's memory transfer ability manifested and they accidentally exchanged 5 years of memories with their mother. This resulted in Tsuru Atae dying a few weeks later, as she could not escape the repeating barrage of her child's memories.
Adolescence
Tsubame trained with Orochimaru in their free time around missions, attempting to learn how to better control their sensory ability. When the war came and teammates started dying, Tsubame let the war consume them and was nothing but a weapon. During a battle with Sunagakure, Tsu met their older sibling Yuu and realized that Sunagakure wanted the war to end, and violence was not the only way to end the war. From there, Tsu pushed for peaceful resolutions and treaty negotiations, but kept the violent reputation they and Ayumu had made as Twin Ikiryo
Adulthood
After returning from a mission to find the Uchiha Clan Tsu had befriended massacred, Tsubame left Konohagakure. After a year or so "haunting" the Land of Fire as a vigilante, they were recruited to the Zodiac Temple by their eldest brother Hanzo. Bound to the Celestial Dragon Seiryu, Tsubame's violent tendencies were curbed and they began work as a Zodiac Disciple pushing for peace between the villages. Tsu's reputation remains among adults in the ninja villages, but most people Naruto's age and younger have only heard of the Twin Ikiryo and don't realize that Tsubame is one of them.