The was a formerly prominent clan in Uzushiogakure. Its members are renown for having bright, red hair, possessing incredibly strong life-forces and chakra, and their prowess in fūinjutsu. Despite the fall of Uzushiogakure and decline of the clan, it never quite went extinct as most of its known members have since resided in Konohagakure. The clan itself was recognised as active again 15 years after the Fourth Shinobi World War.
The name "Uzumaki" can either mean "whirlpool" or "maelstrom".
Red hair was a common trait amongst Uzumaki Clan members.
Tsunade and Nawaki are descendants of the Uzumaki Clan through their grandmother.
Due to Naruto Uzumaki having children with Hinata Hyūga, his direct descendants have the potential to awaken the Byakugan.
Menma Namikaze, an Infinite Tsukuyomi counterpart of Naruto Uzumaki, is a descendant of the Uzumaki Clan by his mother.