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The was a clan of bee users from Iwagakure who were once very well-known and revered. Suzumebachi claims that the First Tsuchikage was a member of the clan.
The members of this clan do not use the generic hand seals used for the Summoning Technique. Instead, they stick their right thumb into the palm of their left hand.
In Konoha Hiden, the beekeeper is heavily suggested to be from the Kamizuru clan: they use bees, wasps, and hornets and are descended from an Iwa clan destroyed many years earlier.