The was one of the clans responsible for founding the first shinobi village: Konohagakure — the other being their rival Uchiha Clan. Although the clan itself no longer appears to exist as a group, the Senju continue to influence Konoha's politics through their philosophy of the Will of Fire and the corresponding interpretation of the role of the Hokage position. As such, three Senju have achieved the position of Hokage.
All known pre-Konoha male Senju's name end in "-ma", more commonly written using the kanji "間", which can refer to space or a room.
Although they owe part of their fame as the "Senju clan of the forest" to the Wood Release, Hashirama Senju was the only clan member known to be capable of utilising it.
The clan's symbol resembles a Vajra, both a symbol and a ritual object present in Buddhism and Hinduism. As a symbol, it represents both indestructible and irresistible force.
Given the clan name’s literal meaning, it is probable that it originated in-universe as an epithet, before eventually evolving into a surname proper.
Naruto Mobile suggests that Senju clansmen often manifest immense physical strength.
According to Kurenai in Konoha Hiden, the Senju often gave honey-wine as a wedding gift.